“Fascia: where it lives and what lives in it.”
Blog #19 - måndag den 7 maj 2018
“Fluid where the Fascia Lives”
count down to Week #19, 13 of May 2018 - British Fascial Symposium lecture
Remember the last time your body was fighting the flu (see Blog 7)? It sucked! The whole body ached. There was no energy. Viruses like to high-jack the DNA and RNA which live inside most of our cells. Strange enough, a mature Red Blood Cell is called a cell, yet it has no nucleus, therefore no DNA nor RNA (funny thing is a virus has no DNA nor RNA either).
One can think the flu virus does this:
One day Billy Blast is swimming in honey. Daddy DNA and Robin RNA live inside Billy Blast. They tell him what to do. Billy Blast being very young and inexperienced listen to Daddy DNA and Robin RNA without question. When a Victorian Gown Virus swims up in front of Billy Blast and says try me on, Billy Blast gladly does so. The Victorian Gown Virus then hypnotizes Billy’s DNA or RNA.
Viruses are very good at this as they have no DNA nor RNA of their own (like a mature RBC). Science is using this greedy behavior to program viruses with good instructions for the cell. It seems to have some promising affects to help fight cancer and more.
Science also using something called basic Fibroblastic Growth Factor to help people with Age Related Macular Degeneration (AMD) to heal the eye and see again. AMD can affect 700,000 people, of those people 10% are the wet form. The method Professor Pete Coffey discusses on the Naked Scientist is targeting the wet form. Like a master chef in a kitchen, an exquisite recipe of a basic Fibroblastic Growth Factor and stem cells are combined to create a Specific Cell Type. The dying part of the eye can be brought back to life.
This all happens in a fluid based system. It is worth revisiting Joint Conference: Acupuncture, Oncology & Fascia from November 2015. Melody Swartz, PhD is at the Panel Discussion and has a side lecture as well. She makes a comment about bacteria; it intrigues me. “…all the bacterial products, you know, billions are turning over every day. And the bacterial cell walls are all lipids. So, they must go into the lymphatics.”
The lymphatic system which Olaus Rudbeck the Elder shared with Queen Christina of Sweden all those years ago, comes back to the research of today. And it is the fluid where the Fascia lives.
Almost there……what lives in Fascia is next
Allissa from Iowa, Living in Sweden
Naked Scientists Senses Month: The Science of Sight
“When vision goes wrong: age-related macular degeneration”
Interview with Professor Pete Coffey, UCL and Moorfields Eye Hospital
Segment - age related macular degeneration 10 April 2018
Pete - It does. In age-related macular degeneration those cells which support the seeing part, the neural retina, die. There’s a number of reasons why that occurs but, effectively, because those cells die the seeing part of the eye no longer has the nutrients, etc. and therefore, over time, it itself dies. What we’ve engineered is making those eye cells, those support cells which are called retinal pigment epithelium, and we put them back in exactly the same format as they are at the back of the eye. So they’re in a single layer, on a carpet of cells, which we’ve surgically then implanted into the back of the eyes of those patients, and they’ve been there now for nearly 2½ years.
Katie - That does not sound like an easy process, so what was involved in creating these cells from these stem cells?
Pete - Actually, it is an easy process. I get very embarrassed about that particular position, because most people who are trying to make a specific cell from a stem cell have gone through a very difficult process, so people who are trying to make cells for Parkinson’s disease, or heart cells, or liver cells. Literally, all we have to do is take one component out of the fluid in which we keep cells and that’s just one component. It’s called basic fibroblast growth factor and then the cells spontaneously make the eye cells that we want.
Fibroblastic Growth Factor (https://en.wikipedia.org/wiki/Fibroblast_growth_factor)
A defining property of fibroblast growth factors (FGFs) is that they bind to heparin and heparan sulfate thus some of them are found to be sequestered in the extracellular matrix of tissues that contains heparan sulfate proteoglycans and they are released locally upon injury or tissue remodeling. In humans, 22 members of the FGF family have been identified, all of which are structurally related signaling molecules:
Panel Discussion, OSHER Joint Conference - Nov. 2015
Osher Center for Integrative Medicine - Published on Feb 17, 2016
Melody Swartz, PhD -
William B. Ogden Professor, Institute of Molecular Engineering, U of Chicago, IL
@ 31:05-31:54 -
“All dietary lipid is taken up exclusively by lymphatics.” “With food, tolerance is taken up by the liver. The liver promotes tolerance to food antigens”
“…all the bacterial products, you know, billions are turning over every day. And the bacterial cell walls are all lipids. So, they must go into the lymphatics.”
Melody Swartz, PhD (Speaker 7): Joint Conference: Acupuncture, Oncology & Fascia
Lymphatics and Cancer Biology
@ 03:02 - “Lymphatic vessels transport fluid and cells from periphery to lymph node…” “if they don’t work, you swell.”
@ 06:27-07:00 - “We also have to remember, there is a lot of stuff in lymph, and it is not just extra cellular fluid that leaked out of the plasma. It is basically information rich. It has all the information of the tissue it drains. You have almost 1000 lymph nodes in the body. Each cluster drains one particular tissue. And it contains all the information from that tissue; the proteins in extra-cellular matrix and the self-antigens even infection to create tolerance to these items.”
@ 09:09-9:34 - “With the lymphatic system, it is not simply a transport system, but it is really an integrated part of all your organ systems. It is part of the circulation, it is part of the metabolism, it is where all lipids are absorbed from your diet, it is part of the immune system, it is even part of your salt balance. And people are finding now, that salt for example, is regulated in skin actively by lymphatic vessels. So it helps with homeostasis.
Medical Definition of self-antigen: any molecule or chemical group of an organism which acts as an antigen in inducing antibody formation in another organism but to which the healthy immune system of the parent organism is tolerant