Blog 20 -
"Somanauts, Find Keys"
Gil Hedley coined the term somanaut. Like an astronaut or cosmonaut, a somanaut is someone who through training explores the inner space of the human body. The following links are doors to new Kingdoms. Choose one or all for a journey beyond structure to the nanoscale world of the small, the numerous, and the beautiful.
Lycka Till - Enjoy the exploration - See you on the other side,
Allissa from Iowa, Living in Sweden
***Interstitium aka: Perifascia: Gil Hedley dissects "the fuzz" on camera.1
somanaut - Published on Mar 28, 2018
In this clip Gil Hedley, Ph.D. of www.gilhedley.com demonstrates with on camera dissection the tissue being heralded in the news and "Nature" as "interstitium," which he calls “perifascia”.
***“Quorum Sensing and its Control” Bonnie L. Bassler
Karolinska Research Lectures: Research Lecture at Nobel Forum
karolinskainstitutet - Published on Nov 9, 2016
@27:25 - “A postdoc in the lab, name X, a physicist said basically, ‘Bonnie this is an optics problem. Let’s just solve it.’ So we did. So what he did was he built a custom confocal microscope. In which every button on the microscope is for imaging tiny objects, he reduced the photo toxicity because mostly what happens is you kill the cells when you try to image them. And then he also wrote these custom algorithms that allowed him to segment the cells and tell who was who. And so now, I will show you what he got. What we can do now, is we can watch these biofilms develop cell by cell - from the founder cell all the way up to about ten or fifteen thousand cells.”
@42:35 - Microbiome cells - one of the substrates they live on is mucin. That is the mucus that covers our intestinal cells.
***Follow Your Gut: Microbiomes and Aging with Rob Knight - Research on Aging
University of California Television (UCTV) [Show ID: 31371] - Published on Mar 6, 2017
Rob Knight explores the unseen microbial world that exists literally right under our noses -- and everywhere else on (and in) our bodies. He discusses the important influence the microbiome may have on the aging process and many end-of-life diseases.
Series: "Stein Institute for Research on Aging”. (Visit: http://www.uctv.tv)
@ 29:34 Question: How can we map our microbiomes?
@ 35:42 Question: How do we start our journeys through this microbiome map?
***Feed Your Microbes - Nurture Your Mind | John Cryan
TEDx Talks - Published on Jul 11, 2017
@2:12 - We are living in a microbial world. These trillions of bacteria that are that are within us and on us are really shaping a lot of what we do for example in terms of genes we are 99% microbial. It's quite humbling. The Human Genome Project is 1%”
@2:45 - 18 months ago, I would have told you that we have 10 times more microbial cells than we do human cells but this is a really fast moving field with changes in technology and mathematical models happening all the time and so more recently this ten-to-one has been downsized to 1.3 to one in the microbes favor.
Bacteria in your gut can change your mind? This is what John wants to bring to the forefront of modern microbiology. Understanding the internal biosphere of each individual has in them today can lead to the creation of a simple capsule can cure bowl illnesses.
He is also a Principal Investigator at the APC Microbiome Institute and was elected a Member of the Royal Irish Academy in 2017. He was a visiting fellow at the Dept Psychiatry, University of Melbourne, Australia, which was followed by postdoctoral fellowships at the University of Pennsylvania, Philadelphia, USA and The Scripps Research Institute, La Jolla, California. He spent four years at the Novartis Institutes for BioMedical Research in Basel Switzerland, as a LabHead prior to joining UCC in 2005.
His current research is focused on understanding the interaction between brain, gut & microbiome, and how it applies to stress, psychiatric and immune-related disorders at key time-windows across the lifespan.
In 2017 he received a Research Mentor Award from the American Gastroenterology Association and the Tom Connor Distinguished Scientist Award from Neuroscience Ireland. He was a TEDMED speaker in 2014 and is currently President-elect of the European Behavioral Pharmacology Society.
***The hidden brain in your skin | Claudia Aguirre
TEDx Talks - Published on Jul 7, 2015
We have all heard of the phrase “beauty is skin deep”, suggesting skin has a rather superficial role in who we are. But what if that is not true? Claudia Aguirre tells us about the "hidden brain" in our skin and the surprising things it reveals about our mental health.
Claudia Aguirre is a Neuroscientist, Skincare Expert, Spokesperson and Lecturer, UCLA Alumni, and TEDMED contributor.